5AM Venture Management, LLC - Portfolio Stock Holdings

5AM Venture Management, LLC disclosed 20 stock positions in a recent SEC 13F filing. $287,891,952 of stock holdings were filed, with the largest holdings including MPLT, TYRA, and TRDA. This filing represented positions held on June 30, 2026, and was filed yesterday.

We estimate the fund has a total AUM of $1,084,259,034 and has 32 employees, per a recent ADV filing. Most of the fund’s AUM appears to come from pooled investment vehicles.